diff --git a/.github/workflows/ci.yml b/.github/workflows/ci.yml
new file mode 100644
index 00000000..96392f58
--- /dev/null
+++ b/.github/workflows/ci.yml
@@ -0,0 +1,110 @@
+name: CI
+
+on:
+  push:
+    branches: [master, stable, next]
+  pull_request:
+    branches: [master, stable, next]
+
+  workflow_dispatch:
+
+jobs:
+  tcc:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+
+      - name: Install dependencies
+        run: sudo apt-get install -y build-essential libtool autoconf automake tcc
+
+      - name: Autogen
+        run: ./autogen.sh -s
+
+      - name: Compilation with tcc
+        run: |
+          env CC=tcc CFLAGS='-w' CPPFLAGS="-DDEV_MODE=1" ./configure --prefix=/tmp --disable-dependency-tracking --disable-shared || cat config.log
+          make -j $(nproc) && make check && make install
+          env CC=tcc CPPFLAGS='-I/tmp/include' LDFLAGS='-L/tmp/lib' LD_LIBRARY_PATH='/tmp/lib' ./test/constcheck.sh
+          make uninstall
+          make distclean
+
+  regular:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+
+      - name: Install dependencies
+        run: sudo apt-get install -y build-essential libtool autoconf automake
+
+      - name: Autogen
+        run: ./autogen.sh -s
+
+      - name: C99 compat check
+        run: |
+          env CPPFLAGS="-DDEV_MODE=1" ./configure --disable-dependency-tracking
+          make -j $(nproc) CFLAGS='-g0' > /dev/null && cp src/libsodium/.libs/libsodium.so lib.so && make clean > /dev/null && make CFLAGS='-g0' CPPFLAGS='-DDEV_MODE=1 -DSODIUM_C99\(X\)=' > /dev/null && cp src/libsodium/.libs/libsodium.so lib-oldc.so && cmp lib.so lib-oldc.so && echo No binary changes && make clean > /dev/null
+          make distcheck
+          make distclean > /dev/null
+
+      - name: Regular compilation
+        run: |
+          env CPPFLAGS="-DDEV_MODE=1" ./configure --disable-dependency-tracking --enable-minimal
+          make -j $(nproc)
+          make check
+          ( echo '#include <sodium.h>' ; echo 'int main(void) { return sodium_init(); }' ) > /tmp/main.c && gcc -DDEV_MODE=1 -Isrc/libsodium/include -Isrc/libsodium/include/sodium $(find src -name '*.c' -o -name '*.S') /tmp/main.c
+          make distclean > /dev/null
+
+  check-globals:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+
+      - name: Install dependencies
+        run: sudo apt-get install -y build-essential libtool autoconf automake
+
+      - name: Autogen
+        run: ./autogen.sh -s
+
+      - name: Check globals
+        run: |
+          test/rename-globals.sh
+
+  other-comp:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+
+      - name: Install dependencies
+        run: sudo apt-get install -y build-essential libtool autoconf automake clang
+
+      - name: Autogen
+        run: ./autogen.sh -s
+
+      - name: Compilation with g++
+        run: |
+          env CC=g++ CPPFLAGS="-DDEV_MODE=1" ./configure --disable-dependency-tracking
+          make -j $(nproc) check
+          make clean > /dev/null
+
+      - name: Compilation with clang
+        run: |
+          env CC=clang CPPFLAGS="-DDEV_MODE=1" ./configure --disable-dependency-tracking
+          make -j $(nproc) check
+          make clean > /dev/null
+
+  other-arch:
+    runs-on: ubuntu-latest
+    steps:
+      - uses: actions/checkout@v2
+
+      - name: Install dependencies
+        run: sudo apt-get install -y build-essential libtool autoconf automake qemu-user-static gcc-powerpc-linux-gnu
+
+      - name: Autogen
+        run: ./autogen.sh -s
+
+      - name: Big-Endian PowerPC compilation
+        run: |
+          env CPPFLAGS="-DDEV_MODE=1" ./configure --disable-dependency-tracking --host=powerpc-linux-gnu
+          make -j $(nproc)
+          make clean > /dev/null